MIF Antagonist (CPSI-1306) Protects against UVB-Induced Squamous Cell Carcinoma
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چکیده
منابع مشابه
Oncogenes and Tumor Suppressors MIF Antagonist (CPSI-1306) Protects against UVB-Induced Squamous Cell Carcinoma
Macrophage migration inhibitory factor (MIF) is a homotrimeric proinflammatory cytokine implicated in chronic inflammatory diseases and malignancies, including cutaneous squamous cell carcinomas (SCC). To determinewhetherMIF inhibition could reduceUVB light–induced inflammation and squamous carcinogenesis, a small-molecule MIF inhibitor (CPSI-1306) was utilized that disrupts homotrimerization. ...
متن کاملMIF antagonist (CPSI-1306) protects against UVB-induced squamous cell carcinoma.
UNLABELLED Macrophage migration inhibitory factor (MIF) is a homotrimeric proinflammatory cytokine implicated in chronic inflammatory diseases and malignancies, including cutaneous squamous cell carcinomas (SCC). To determine whether MIF inhibition could reduce UVB light-induced inflammation and squamous carcinogenesis, a small-molecule MIF inhibitor (CPSI-1306) was utilized that disrupts homot...
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ژورنال
عنوان ژورنال: Molecular Cancer Research
سال: 2014
ISSN: 1541-7786,1557-3125
DOI: 10.1158/1541-7786.mcr-14-0255-t